Propargyl-PEG7-acid
Based on 1 Customer Validation
Propargyl-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG7-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- CAS No.: 2093154-00-6
- Formule: C18H32O9
- Masse moléculaire:392.44
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Stockage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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HY-130481
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HY-130379
Propargyl-PEG8-acidADC/PROTAC Linker -
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Propargyl-PEG1-acidPROTAC Linkers -
HY-118764
Propargyl-PEG2-acidPROTAC/ADC Linker -
HY-101157
Propargyl-PEG5-acidADC Linker -
HY-126975
Propargyl-PEG3-acidADC/PROTAC Linker -
HY-130386
Propargyl-PEG6-acidADC/PROTAC Linker -
HY-140020
Propargyl-PEG10-acidPEG Derivative -
HY-101157R
Propargyl-PEG5-acid (Standard)ADC Linker
Voir tous les produits spécifiques à Isoform ADC Linkers
MoreVoir tous les produits spécifiques à Isoform PROTAC Linkers
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Activité biologique
Description
IC50 & Target
[1]|
Cleavable Linker |
PEGs |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2093154-00-6
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Appearance Liquid
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Masse moléculaire 392.44
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Formule C18H32O9
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Color Light yellow to yellow
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SMILES
C#CCOCCOCCOCCOCCOCCOCCOCCC(O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Pureté et documentation
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Fiche technique (261 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Propargyl-PEG7-acid Related Classifications
HY-130383 Related Classifications
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