1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. Desmethyl Vc-seco-DUBA

Desmethyl Vc-seco-DUBA 

Cat. No.: HY-131085
Handling Instructions

Desmethyl Vc-seco-DUBA consists a cleavable ADC linker (Desmethyl Vc-seco) and a DNA alkylating agent (DUBA). Desmethyl Vc-seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Desmethyl Vc-seco-DUBA Chemical Structure

Desmethyl Vc-seco-DUBA Chemical Structure

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Description

Desmethyl Vc-seco-DUBA consists a cleavable ADC linker (Desmethyl Vc-seco) and a DNA alkylating agent (DUBA). Desmethyl Vc-seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Duocarmycins

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Molecular Weight

1317.79

Formula

C₆₄H₇₃ClN₁₂O₁₇

SMILES

O=C(N(CCN(CCOCCO)C(OC1=CC2=C(C3=CC=CC=C31)[[email protected]](CCl)CN2C(C4=CN5C=C(NC(C6=CC=C(O)C=C6)=O)C=CC5=N4)=O)=O)C)OCC7=CC=C(C=C7)NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(OCCOCCN8C(C=CC8=O)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Desmethyl Vc-seco-DUBADrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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Product name:
Desmethyl Vc-seco-DUBA
Cat. No.:
HY-131085
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