1. Cell Cycle/DNA Damage
    Cytoskeleton
    Antibody-drug Conjugate/ADC Related
  2. Microtubule/Tubulin
    Drug-Linker Conjugates for ADC
  3. MC-betaglucuronide-MMAE-2

MC-betaglucuronide-MMAE-2 

Cat. No.: HY-136321
Handling Instructions

MC-betaglucuronide-MMAE-2 is a drug-linker conjugate for ADC with potent antitumor activity by using MMAE (a tubulin polymerization inhibitor), linked via the cleavable ADC linker MC-betaglucuronide.

For research use only. We do not sell to patients.

MC-betaglucuronide-MMAE-2 Chemical Structure

MC-betaglucuronide-MMAE-2 Chemical Structure

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Description

MC-betaglucuronide-MMAE-2 is a drug-linker conjugate for ADC with potent antitumor activity by using MMAE (a tubulin polymerization inhibitor), linked via the cleavable ADC linker MC-betaglucuronide.

IC50 & Target

Auristatin

 

Molecular Weight

1296.46

Formula

C₆₃H₉₃N₉O₂₀

SMILES

O[[email protected]]1[[email protected]](O)[[email protected]@H](O)[[email protected]](OC2=C(NC(CCNC([[email protected]](CN)N3C(C=CC3=O)=O)=O)=O)C=C(COC(N(C)[[email protected]@H](C(C)C)C(N[[email protected]](C(N(C)[[email protected]@H]([[email protected]](CC)C)[[email protected]](OC)CC(N4[[email protected]]([[email protected]](OC)[[email protected]@H](C)C(N[[email protected]](C)[[email protected]@H](O)C5=CC=CC=C5)=O)CCC4)=O)=O)C(C)C)=O)=O)C=C2)O[[email protected]@H]1C(O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

MC-betaglucuronide-MMAE-2Microtubule/TubulinDrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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Product name:
MC-betaglucuronide-MMAE-2
Cat. No.:
HY-136321
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