MC-betaglucuronide-MMAE-2
Based on 1 Customer Validation
MC-betaglucuronide-MMAE-2 is a agent-linker conjugate for ADC with potent antitumor activity by using MMAE (a tubulin polymerization inhibitor), linked via the cleavable ADC linker MC-betaglucuronide.
For research use only. We do not sell to patients.
- Purity: 95.00%
- CAS No.: 1703778-81-7
- Formula: C63H93N9O20
- Molecular Weight:1296.46
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Storage:Powder -20°C, 3 years , 4°C, 2 years
* The compound is unstable in solutions, freshly prepared is recommended.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
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Auristatin |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1703778-81-7
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Appearance Solid
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Molecular Weight 1296.46
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Formula C63H93N9O20
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Color White to off-white
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SMILES
O[C@H]1[C@H](O)[C@@H](O)[C@H](OC2=C(NC(CCNC([C@H](CN)N3C(C=CC3=O)=O)=O)=O)C=C(COC(N(C)[C@@H](C(C)C)C(N[C@H](C(N(C)[C@@H]([C@H](CC)C)[C@H](OC)CC(N4[C@H]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C5=CC=CC=C5)=O)CCC4)=O)=O)C(C)C)=O)=O)C=C2)O[C@@H]1C(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years * The compound is unstable in solutions, freshly prepared is recommended.
Solvent & Solubility
DMSO : ≥ 100 mg/mL (77.13 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (244 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.7713 mL | 3.8567 mL | 7.7133 mL | 19.2833 mL |
| 5 mM | 0.1543 mL | 0.7713 mL | 1.5427 mL | 3.8567 mL | |
| 10 mM | 0.0771 mL | 0.3857 mL | 0.7713 mL | 1.9283 mL | |
| 15 mM | 0.0514 mL | 0.2571 mL | 0.5142 mL | 1.2856 mL | |
| 20 mM | 0.0386 mL | 0.1928 mL | 0.3857 mL | 0.9642 mL | |
| 25 mM | 0.0309 mL | 0.1543 mL | 0.3085 mL | 0.7713 mL | |
| 30 mM | 0.0257 mL | 0.1286 mL | 0.2571 mL | 0.6428 mL | |
| 40 mM | 0.0193 mL | 0.0964 mL | 0.1928 mL | 0.4821 mL | |
| 50 mM | 0.0154 mL | 0.0771 mL | 0.1543 mL | 0.3857 mL | |
| 60 mM | 0.0129 mL | 0.0643 mL | 0.1286 mL | 0.3214 mL |
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