Val-Ala-PAB
Based on 1 Customer Validation
Val-Ala-PAB is a cleavable ADC linker that can be used for ADCs synthesis.
For research use only. We do not sell to patients.
- Purity: 99.70%
- CAS No.: 1343476-44-7
- Formula: C15H23N3O3
- Molecular Weight:293.37
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1343476-44-7
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Appearance Solid
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Molecular Weight 293.37
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Formula C15H23N3O3
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Color White to light yellow
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SMILES
CC(C)[C@H](N)C(N[C@@H](C)C(NC1=CC=C(C=C1)CO)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 116.67 mg/mL (397.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4087 mL | 17.0435 mL | 34.0870 mL | 85.2175 mL |
| 5 mM | 0.6817 mL | 3.4087 mL | 6.8174 mL | 17.0435 mL | |
| 10 mM | 0.3409 mL | 1.7043 mL | 3.4087 mL | 8.5217 mL | |
| 15 mM | 0.2272 mL | 1.1362 mL | 2.2725 mL | 5.6812 mL | |
| 20 mM | 0.1704 mL | 0.8522 mL | 1.7043 mL | 4.2609 mL | |
| 25 mM | 0.1363 mL | 0.6817 mL | 1.3635 mL | 3.4087 mL | |
| 30 mM | 0.1136 mL | 0.5681 mL | 1.1362 mL | 2.8406 mL | |
| 40 mM | 0.0852 mL | 0.4261 mL | 0.8522 mL | 2.1304 mL | |
| 50 mM | 0.0682 mL | 0.3409 mL | 0.6817 mL | 1.7043 mL | |
| 60 mM | 0.0568 mL | 0.2841 mL | 0.5681 mL | 1.4203 mL | |
| 80 mM | 0.0426 mL | 0.2130 mL | 0.4261 mL | 1.0652 mL | |
| 100 mM | 0.0341 mL | 0.1704 mL | 0.3409 mL | 0.8522 mL |
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