2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Mal-amido-PEG2-NHS ester

Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

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Mal-amido-PEG2-NHS ester Chemical Structure

Mal-amido-PEG2-NHS ester Chemical Structure

CAS No. : 955094-26-5

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Based on 1 publication(s) in Google Scholar

Mal-amido-PEG2-NHS ester Related Antibodies

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Description

Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

IC50 & Target

Non-cleavable Linker

 

Molecular Weight

425.39

Formula

C18H23N3O9
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(CCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)ON2C(CCC2=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.32%

COA (245 KB) HNMR (120 KB) RP-HPLC (196 KB)

Handling Instructions (2659 KB)
References
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Mal-amido-PEG2-NHS ester Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mal-amido-PEG2-NHS ester955094-26-5ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Mal-amido-PEG2-NHS ester
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