m-PEG10-alcohol
Based on 1 Customer Validation
m-PEG10-alcohol (Decaethylene glycol monomethyl ether) is a non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). m-PEG10-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 27425-92-9
- Fòrmula: C21H44O11
- Peso molecular:472.57
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Almacenamiento:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Help & FAQs
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HY-141217
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m-PEG2-CH2CH2COOH
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MoreVer todos los productos específicos de isoformas PROTAC Linkers
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
PEGs |
Non-cleavable Linker |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 27425-92-9
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Appearance <19°C Solid,>19°C Liquid
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Peso molecular 472.57
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Fòrmula C21H44O11
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Color Light yellow to yellow
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SMILES
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
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Synonyms
Decaethylene glycol monomethyl ether
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (261 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
m-PEG10-alcohol Related Classifications
HY-141218 Related Classifications
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