Mal-PEG2-bis-PEG3-BCN
Based on 1 Customer Validation
Mal-PEG2-bis-PEG3-BCN is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-bis-PEG3-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Purity: 97.33%
- CAS No.: 2882973-13-7
- Formula: C61H95N7O20
- Molecular Weight:1246.44
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2882973-13-7
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Appearance Solid-Liquid Mixture
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Molecular Weight 1246.44
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Formula C61H95N7O20
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Color Light yellow to yellow
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SMILES
[H][C@@]12[C@@](CCC#CCC2)([H])[C@@H]1COC(NCCOCCOCCOCCNC(CCOCC(NC(CCOCCOCCNC(CCN3C(C=CC3=O)=O)=O)=O)COCCC(NCCOCCOCCOCCNC(OC[C@@H]4[C@@]5(CCC#CCC[C@@]54[H])[H])=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (80.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.8023 mL | 4.0114 mL | 8.0228 mL | 20.0571 mL |
| 5 mM | 0.1605 mL | 0.8023 mL | 1.6046 mL | 4.0114 mL | |
| 10 mM | 0.0802 mL | 0.4011 mL | 0.8023 mL | 2.0057 mL | |
| 15 mM | 0.0535 mL | 0.2674 mL | 0.5349 mL | 1.3371 mL | |
| 20 mM | 0.0401 mL | 0.2006 mL | 0.4011 mL | 1.0029 mL | |
| 25 mM | 0.0321 mL | 0.1605 mL | 0.3209 mL | 0.8023 mL | |
| 30 mM | 0.0267 mL | 0.1337 mL | 0.2674 mL | 0.6686 mL | |
| 40 mM | 0.0201 mL | 0.1003 mL | 0.2006 mL | 0.5014 mL | |
| 50 mM | 0.0160 mL | 0.0802 mL | 0.1605 mL | 0.4011 mL | |
| 60 mM | 0.0134 mL | 0.0669 mL | 0.1337 mL | 0.3343 mL | |
| 80 mM | 0.0100 mL | 0.0501 mL | 0.1003 mL | 0.2507 mL |
Mal-PEG2-bis-PEG3-BCN Related Classifications
HY-136060 Related Classifications
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