1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. Mc-Val-Cit-PAB-Cl

Mc-Val-Cit-PAB-Cl 

Cat. No.: HY-112099
Handling Instructions

Mc-Val-Cit-PAB-Cl is an ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).

For research use only. We do not sell to patients.

Mc-Val-Cit-PAB-Cl Chemical Structure

Mc-Val-Cit-PAB-Cl Chemical Structure

CAS No. : 1639351-92-0

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Description

Mc-Val-Cit-PAB-Cl is an ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).

IC50 & Target

Alkyl/ether

 

Molecular Weight

591.10

Formula

C₂₈H₃₉ClN₆O₆

CAS No.

1639351-92-0

SMILES

O=C(N1CCCCCC(N[[email protected]@H](C(C)C)C(N[[email protected]@H](CCCNC(N)=O)C(NC2=CC=C(CCl)C=C2)=O)=O)=O)C=CC1=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Mc-Val-Cit-PAB-Cl
Cat. No.:
HY-112099
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