H-Asp-Gly-OH
Based on 1 Customer Validation
H-Asp-Gly-OH is a cleavable ADC linker.
For research use only. We do not sell to patients.
- Purity: 98.04%
- CAS No.: 3790-51-0
- Formula: C6H10N2O5
- Molecular Weight:190.15
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
Biological Activity
Cleavable Linker
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDCK | EC50 |
0.44 mM
Compound: 13
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Activation of human PEPT1 expressed in MDCK cells
Activation of human PEPT1 expressed in MDCK cells
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[PMID: 16759105] |
| MDCK | IC50 |
0.81 mM
Compound: 13
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Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
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[PMID: 16759105] |
Chemical Information
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CAS No. 3790-51-0
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Appearance Solid
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Molecular Weight 190.15
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Formula C6H10N2O5
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Color White to off-white
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SMILES
O=C(O)CNC([C@@H](N)CC(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 50 mg/mL (262.95 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (241 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.2590 mL | 26.2950 mL | 52.5901 mL | 131.4752 mL |
| 5 mM | 1.0518 mL | 5.2590 mL | 10.5180 mL | 26.2950 mL | |
| 10 mM | 0.5259 mL | 2.6295 mL | 5.2590 mL | 13.1475 mL | |
| 15 mM | 0.3506 mL | 1.7530 mL | 3.5060 mL | 8.7650 mL | |
| 20 mM | 0.2630 mL | 1.3148 mL | 2.6295 mL | 6.5738 mL | |
| 25 mM | 0.2104 mL | 1.0518 mL | 2.1036 mL | 5.2590 mL | |
| 30 mM | 0.1753 mL | 0.8765 mL | 1.7530 mL | 4.3825 mL | |
| 40 mM | 0.1315 mL | 0.6574 mL | 1.3148 mL | 3.2869 mL | |
| 50 mM | 0.1052 mL | 0.5259 mL | 1.0518 mL | 2.6295 mL | |
| 60 mM | 0.0877 mL | 0.4383 mL | 0.8765 mL | 2.1913 mL | |
| 80 mM | 0.0657 mL | 0.3287 mL | 0.6574 mL | 1.6434 mL | |
| 100 mM | 0.0526 mL | 0.2630 mL | 0.5259 mL | 1.3148 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
H-Asp-Gly-OH Related Classifications
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