DTSSP Crosslinker
Based on 1 Customer Validation
DTSSP Crosslinker is a crosslinker reactive with primary amines. DTSSP Crosslinker is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 81069-02-5
- Formula: C14H16N2O14S4
- Molecular Weight:564.54
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Disulfide Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 81069-02-5
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Appearance Solid
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Molecular Weight 564.54
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Formula C14H16N2O14S4
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Color White to off-white
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SMILES
O=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCSSCCC(ON2C(C(S(=O)(O)=O)CC2=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 125 mg/mL (221.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7714 mL | 8.8568 mL | 17.7135 mL | 44.2838 mL |
| 5 mM | 0.3543 mL | 1.7714 mL | 3.5427 mL | 8.8568 mL | |
| 10 mM | 0.1771 mL | 0.8857 mL | 1.7714 mL | 4.4284 mL | |
| 15 mM | 0.1181 mL | 0.5905 mL | 1.1809 mL | 2.9523 mL | |
| 20 mM | 0.0886 mL | 0.4428 mL | 0.8857 mL | 2.2142 mL | |
| 25 mM | 0.0709 mL | 0.3543 mL | 0.7085 mL | 1.7714 mL | |
| 30 mM | 0.0590 mL | 0.2952 mL | 0.5905 mL | 1.4761 mL | |
| 40 mM | 0.0443 mL | 0.2214 mL | 0.4428 mL | 1.1071 mL | |
| 50 mM | 0.0354 mL | 0.1771 mL | 0.3543 mL | 0.8857 mL | |
| 60 mM | 0.0295 mL | 0.1476 mL | 0.2952 mL | 0.7381 mL | |
| 80 mM | 0.0221 mL | 0.1107 mL | 0.2214 mL | 0.5535 mL | |
| 100 mM | 0.0177 mL | 0.0886 mL | 0.1771 mL | 0.4428 mL |
DTSSP Crosslinker Related Classifications
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