Mal-C2-NHS ester
Based on 1 Customer Validation
Mal-C2-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 99.30%
- CAS No.: 103750-03-4
- Formula: C13H14N2O6
- Molecular Weight:294.26
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Non-cleavable Linker |
Mal-C2-NHS ester is a non-degradable ADC linker used for the synthesis of antibody-drug conjugates (ADCs)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 103750-03-4
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Appearance Solid
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Molecular Weight 294.26
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Formula C13H14N2O6
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Color White to light yellow
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SMILES
O=C(ON1C(CCC1=O)=O)CCCCN2C(C=CC2=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (339.84 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3984 mL | 16.9918 mL | 33.9836 mL | 84.9589 mL |
| 5 mM | 0.6797 mL | 3.3984 mL | 6.7967 mL | 16.9918 mL | |
| 10 mM | 0.3398 mL | 1.6992 mL | 3.3984 mL | 8.4959 mL | |
| 15 mM | 0.2266 mL | 1.1328 mL | 2.2656 mL | 5.6639 mL | |
| 20 mM | 0.1699 mL | 0.8496 mL | 1.6992 mL | 4.2479 mL | |
| 25 mM | 0.1359 mL | 0.6797 mL | 1.3593 mL | 3.3984 mL | |
| 30 mM | 0.1133 mL | 0.5664 mL | 1.1328 mL | 2.8320 mL | |
| 40 mM | 0.0850 mL | 0.4248 mL | 0.8496 mL | 2.1240 mL | |
| 50 mM | 0.0680 mL | 0.3398 mL | 0.6797 mL | 1.6992 mL | |
| 60 mM | 0.0566 mL | 0.2832 mL | 0.5664 mL | 1.4160 mL | |
| 80 mM | 0.0425 mL | 0.2124 mL | 0.4248 mL | 1.0620 mL | |
| 100 mM | 0.0340 mL | 0.1699 mL | 0.3398 mL | 0.8496 mL |
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