GGFG-PAB-MMAE
Based on 1 Customer Validation
GGFG-PAB-MMAE (Comp 58054-1) is a drug-linker conjugate for ADC. GGFG-PAB-MMAE contains the ADC linker (GGFG-PAB) and a potent tubulin polymerization inhibitor MMAE (HY-15162).
For research use only. We do not sell to patients.
- Purity: 99.33%
- CAS No.: 3049886-19-0
- Formula: C62H92N10O13
- Molecular Weight:1185.45
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
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Auristatin |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3049886-19-0
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Appearance Solid
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Molecular Weight 1185.45
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Formula C62H92N10O13
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Color White to light yellow
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SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC(CNC([C@@H](NC(CNC(CN)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (84.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8436 mL | 4.2178 mL | 8.4356 mL | 21.0890 mL |
| 5 mM | 0.1687 mL | 0.8436 mL | 1.6871 mL | 4.2178 mL | |
| 10 mM | 0.0844 mL | 0.4218 mL | 0.8436 mL | 2.1089 mL | |
| 15 mM | 0.0562 mL | 0.2812 mL | 0.5624 mL | 1.4059 mL | |
| 20 mM | 0.0422 mL | 0.2109 mL | 0.4218 mL | 1.0545 mL | |
| 25 mM | 0.0337 mL | 0.1687 mL | 0.3374 mL | 0.8436 mL | |
| 30 mM | 0.0281 mL | 0.1406 mL | 0.2812 mL | 0.7030 mL | |
| 40 mM | 0.0211 mL | 0.1054 mL | 0.2109 mL | 0.5272 mL | |
| 50 mM | 0.0169 mL | 0.0844 mL | 0.1687 mL | 0.4218 mL | |
| 60 mM | 0.0141 mL | 0.0703 mL | 0.1406 mL | 0.3515 mL | |
| 80 mM | 0.0105 mL | 0.0527 mL | 0.1054 mL | 0.2636 mL |
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