Amino-PEG6-amido-bis-PEG5-N3
Based on 1 Customer Validation
Amino-PEG6-amido-bis-PEG5-N3 is a cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG6-amido-bis-PEG5-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
For research use only. We do not sell to patients.
- Formula: C48H94N10O21
- Molecular Weight:1147.31
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Oil
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Molecular Weight 1147.31
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Formula C48H94N10O21
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Color Colorless to light yellow
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SMILES
NCCOCCOCCOCCOCCOCCOCCC(NC(COCCC(NCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)COCCC(NCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (87.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8716 mL | 4.3580 mL | 8.7160 mL | 21.7901 mL |
| 5 mM | 0.1743 mL | 0.8716 mL | 1.7432 mL | 4.3580 mL | |
| 10 mM | 0.0872 mL | 0.4358 mL | 0.8716 mL | 2.1790 mL | |
| 15 mM | 0.0581 mL | 0.2905 mL | 0.5811 mL | 1.4527 mL | |
| 20 mM | 0.0436 mL | 0.2179 mL | 0.4358 mL | 1.0895 mL | |
| 25 mM | 0.0349 mL | 0.1743 mL | 0.3486 mL | 0.8716 mL | |
| 30 mM | 0.0291 mL | 0.1453 mL | 0.2905 mL | 0.7263 mL | |
| 40 mM | 0.0218 mL | 0.1090 mL | 0.2179 mL | 0.5448 mL | |
| 50 mM | 0.0174 mL | 0.0872 mL | 0.1743 mL | 0.4358 mL | |
| 60 mM | 0.0145 mL | 0.0726 mL | 0.1453 mL | 0.3632 mL | |
| 80 mM | 0.0109 mL | 0.0545 mL | 0.1090 mL | 0.2724 mL |
Amino-PEG6-amido-bis-PEG5-N3 Related Classifications
HY-130957 Related Classifications
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