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Cat. No.: HY-175881

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3-Formyl-L-tyrosine-oxime-Val-Cit-PAPB

3-Formyl-L-tyrosine-oxime-Val-Cit-PAPB is an ADC linker that can be used for the synthesis of the TUB-010 drug linker (HY-175884).

For research use only. We do not sell to patients.

Formula: C₃₁H₄₁N₇O₁₁
Molecular Weight:687.70

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

3-Formyl-L-tyrosine-oxime-Val-Cit-PAPB Chemical Structure

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Use of MCE Products

One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity

Description

3-Formyl-L-tyrosine-oxime-Val-Cit-PAPB is an ADC linker that can be used for the synthesis of the TUB-010 drug linker (HY-175884)^[1].

All ADC Linkers Isoforms :

Chemical Information

Molecular Weight 687.70
Formula C₃₁H₄₁N₇O₁₁
SMILES

O=C(O)[C@@H](N)CC1=CC=C(O)C(/C=N/OCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(O)=O)C=C2)=O)=O)=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gerlach M, et al. TUB-010, a novel anti-CD30 antibody-drug conjugate based on Tub-tag technology, widens the therapeutic window by reducing toxicity while maintaining high efficacy. Mol Cancer Ther. 2025 Aug 20. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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3-Formyl-L-tyrosine-oxime-Val-Cit-PAPB

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3-Formyl-L-tyrosine-oxime-Val-Cit-PAPB

All ADC Linkers Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

3-Formyl-L-tyrosine-oxime-Val-Cit-PAPB Related Classifications

HY-175881 Related Classifications

Bioz

Keywords

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