Ac-Lys-Val-Cit-PABC-MMAE
Based on 1 Customer Validation
Ac-Lys-Val-Cit-PABC-MMAE is a agent-linker conjugate for ADC. Ac-Lys-Val-Cit-PABC-MMAE contains the ADC linker (peptide Ac-Lys-Val-Cit-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162).
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 1650569-89-3
- Formula: C66H108N12O14
- Molecular Weight:1293.64
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
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Auristatin |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1650569-89-3
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Appearance Solid
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Molecular Weight 1293.64
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Formula C66H108N12O14
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Color White to off-white
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SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : ≥ 200 mg/mL (154.60 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7730 mL | 3.8651 mL | 7.7301 mL | 19.3253 mL |
| 5 mM | 0.1546 mL | 0.7730 mL | 1.5460 mL | 3.8651 mL | |
| 10 mM | 0.0773 mL | 0.3865 mL | 0.7730 mL | 1.9325 mL | |
| 15 mM | 0.0515 mL | 0.2577 mL | 0.5153 mL | 1.2884 mL | |
| 20 mM | 0.0387 mL | 0.1933 mL | 0.3865 mL | 0.9663 mL | |
| 25 mM | 0.0309 mL | 0.1546 mL | 0.3092 mL | 0.7730 mL | |
| 30 mM | 0.0258 mL | 0.1288 mL | 0.2577 mL | 0.6442 mL | |
| 40 mM | 0.0193 mL | 0.0966 mL | 0.1933 mL | 0.4831 mL | |
| 50 mM | 0.0155 mL | 0.0773 mL | 0.1546 mL | 0.3865 mL | |
| 60 mM | 0.0129 mL | 0.0644 mL | 0.1288 mL | 0.3221 mL | |
| 80 mM | 0.0097 mL | 0.0483 mL | 0.0966 mL | 0.2416 mL | |
| 100 mM | 0.0077 mL | 0.0387 mL | 0.0773 mL | 0.1933 mL |
Ac-Lys-Val-Cit-PABC-MMAE Related Classifications
HY-147286 Related Classifications
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