2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. Ac-Lys-Val-Cit-PABC-MMAE

Ac-Lys-Val-Cit-PABC-MMAE 

Cat. No.: HY-147286 Purity: 99.99%
COA Handling Instructions

Ac-Lys-Val-Cit-PABC-MMAE is a drug-linker conjugate for ADC. Ac-Lys-Val-Cit-PABC-MMAE contains the ADC linker (peptide Ac-Lys-Val-Cit-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162).

For research use only. We do not sell to patients.

Ac-Lys-Val-Cit-PABC-MMAE Chemical Structure

Ac-Lys-Val-Cit-PABC-MMAE Chemical Structure

CAS No. : 1650569-89-3

Size Price Stock Quantity
10 mg USD 950 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1900 In-stock
Estimated Time of Arrival: December 31
50 mg USD 3050 In-stock
Estimated Time of Arrival: December 31
100 mg USD 4800 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Ac-Lys-Val-Cit-PABC-MMAE:

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Description

Ac-Lys-Val-Cit-PABC-MMAE is a drug-linker conjugate for ADC. Ac-Lys-Val-Cit-PABC-MMAE contains the ADC linker (peptide Ac-Lys-Val-Cit-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1].

IC50 & Target

Auristatin

 

Molecular Weight

1293.64

Appearance

Solid

Formula

C66H108N12O14
CAS No.
SMILES

O[[email protected]@H](C1=CC=CC=C1)[[email protected]@H](C)NC([[email protected]](C)[[email protected]]([[email protected]@]2([H])N(CCC2)C(C[[email protected]@H](OC)[[email protected]]([[email protected]@H](C)CC)N(C)C([[email protected]](C(C)C)NC([[email protected]](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC([[email protected]@H](NC(C)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)OC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro: 

DMSO : ≥ 200 mg/mL (154.60 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7730 mL 3.8651 mL 7.7301 mL
5 mM 0.1546 mL 0.7730 mL 1.5460 mL
10 mM 0.0773 mL 0.3865 mL 0.7730 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Keywords:

Ac-Lys-Val-Cit-PABC-MMAE1650569-89-3Drug-Linker Conjugates for ADCcancerInhibitorinhibitorinhibit

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