Ac-Lys-Val-Cit-PABC-MMAE formic
Based on 1 Customer Validation
Ac-Lys-Val-Cit-PABC-MMAE (formic) is a agent-linker conjugate for ADC. Ac-Lys-Val-Cit-PABC-MMAE contains the ADC linker (peptide Ac-Lys-Val-Cit-PABC) and a potent tubulin polymerization inhibitorMonomethyl auristatin E (HY-15162).
For research use only. We do not sell to patients.
- Purity: 99.96%
- Formula: C67H110N12O16
- Molecular Weight:1339.66
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 1339.66
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Formula C67H110N12O16
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Color White to off-white
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SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)OC)=O.OC=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 200 mg/mL (149.29 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7465 mL | 3.7323 mL | 7.4646 mL | 18.6615 mL |
| 5 mM | 0.1493 mL | 0.7465 mL | 1.4929 mL | 3.7323 mL | |
| 10 mM | 0.0746 mL | 0.3732 mL | 0.7465 mL | 1.8661 mL | |
| 15 mM | 0.0498 mL | 0.2488 mL | 0.4976 mL | 1.2441 mL | |
| 20 mM | 0.0373 mL | 0.1866 mL | 0.3732 mL | 0.9331 mL | |
| 25 mM | 0.0299 mL | 0.1493 mL | 0.2986 mL | 0.7465 mL | |
| 30 mM | 0.0249 mL | 0.1244 mL | 0.2488 mL | 0.6220 mL | |
| 40 mM | 0.0187 mL | 0.0933 mL | 0.1866 mL | 0.4665 mL | |
| 50 mM | 0.0149 mL | 0.0746 mL | 0.1493 mL | 0.3732 mL | |
| 60 mM | 0.0124 mL | 0.0622 mL | 0.1244 mL | 0.3110 mL | |
| 80 mM | 0.0093 mL | 0.0467 mL | 0.0933 mL | 0.2333 mL | |
| 100 mM | 0.0075 mL | 0.0373 mL | 0.0746 mL | 0.1866 mL |
Ac-Lys-Val-Cit-PABC-MMAE formic Related Classifications
HY-147286A Related Classifications
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