MC-VC-PAB-Cyclohexanediamine-Thailanstatin A
MC-VC-PAB-Cyclohexanediamine-Thailanstatin A is a Spliceostatin (HY-16466) analog, and a drug-linker conjugates for ADC, consisting of ADC Cytotoxin Thailanstatin A (HY-129589) and cleavable ADC linker (MC-vc-PAB). MC-VC-PAB-Cyclohexanediamine-Thailanstatin A can be used for ADC synthesis.
For research use only. We do not sell to patients.
- CAS No.: 1609108-96-4
- Formula: C63H91N9O16
- Molecular Weight:1230.45
-
Storage:
-80°C, protect from light, stored under nitrogen
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
Chemical Information
-
CAS No. 1609108-96-4
-
Appearance Solid
-
Molecular Weight 1230.45
-
Formula C63H91N9O16
-
Color White to off-white
-
SMILES
O[C@H]1[C@@]2(C[C@H](O[C@@H]1/C=C/C(C)=C/C[C@H]3[C@H](C[C@H]([C@H](O3)C)NC(/C=C\[C@H](C)OC(C)=O)=O)C)CC(N[C@@H]4CC[C@H](CC4)NC(OCC5=CC=C(C=C5)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN6C(C=CC6=O)=O)=O)=O)=O)=O)=O)CO2
-
Shipping
Shipping with dry ice.
-
Storage
-80°C, protect from light, stored under nitrogen
Solvent & Solubility
In Vitro:
DMSO : 85 mg/mL (69.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (269 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8127 mL | 4.0636 mL | 8.1271 mL | 20.3178 mL |
| 5 mM | 0.1625 mL | 0.8127 mL | 1.6254 mL | 4.0636 mL | |
| 10 mM | 0.0813 mL | 0.4064 mL | 0.8127 mL | 2.0318 mL | |
| 15 mM | 0.0542 mL | 0.2709 mL | 0.5418 mL | 1.3545 mL | |
| 20 mM | 0.0406 mL | 0.2032 mL | 0.4064 mL | 1.0159 mL | |
| 25 mM | 0.0325 mL | 0.1625 mL | 0.3251 mL | 0.8127 mL | |
| 30 mM | 0.0271 mL | 0.1355 mL | 0.2709 mL | 0.6773 mL | |
| 40 mM | 0.0203 mL | 0.1016 mL | 0.2032 mL | 0.5079 mL | |
| 50 mM | 0.0163 mL | 0.0813 mL | 0.1625 mL | 0.4064 mL | |
| 60 mM | 0.0135 mL | 0.0677 mL | 0.1355 mL | 0.3386 mL |
MC-VC-PAB-Cyclohexanediamine-Thailanstatin A Related Classifications
HY-153601 Related Classifications
Powered by Bioz