Folate-PEG3-amine
Based on 1 Customer Validation
Folate-PEG3-amine is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 99.69%
- CAS No.: 710323-40-3
- Formula: C27H37N9O8
- Molecular Weight:615.64
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 710323-40-3
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Appearance Solid
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Molecular Weight 615.64
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Formula C27H37N9O8
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Color Light yellow to yellow
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SMILES
O=C(O)[C@@H](NC(C1=CC=C(NCC2=CN=C3NC(N)=NC(C3=N2)=O)C=C1)=O)CCC(NCCOCCOCCOCCN)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (162.43 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6243 mL | 8.1216 mL | 16.2433 mL | 40.6081 mL |
| 5 mM | 0.3249 mL | 1.6243 mL | 3.2487 mL | 8.1216 mL | |
| 10 mM | 0.1624 mL | 0.8122 mL | 1.6243 mL | 4.0608 mL | |
| 15 mM | 0.1083 mL | 0.5414 mL | 1.0829 mL | 2.7072 mL | |
| 20 mM | 0.0812 mL | 0.4061 mL | 0.8122 mL | 2.0304 mL | |
| 25 mM | 0.0650 mL | 0.3249 mL | 0.6497 mL | 1.6243 mL | |
| 30 mM | 0.0541 mL | 0.2707 mL | 0.5414 mL | 1.3536 mL | |
| 40 mM | 0.0406 mL | 0.2030 mL | 0.4061 mL | 1.0152 mL | |
| 50 mM | 0.0325 mL | 0.1624 mL | 0.3249 mL | 0.8122 mL | |
| 60 mM | 0.0271 mL | 0.1354 mL | 0.2707 mL | 0.6768 mL | |
| 80 mM | 0.0203 mL | 0.1015 mL | 0.2030 mL | 0.5076 mL | |
| 100 mM | 0.0162 mL | 0.0812 mL | 0.1624 mL | 0.4061 mL |
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