Dap-NE hydrochloride
Based on 1 Customer Validation
Dap-NE hydrochloride is a dipeptide hydrochloride and a cleavable ADC Linker.Dap-NE hydrochloride can be used to connect Antibody and toxin molecules (Cytotoxin) to synthesize Antibody-Drug Conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 100%
- CAS No.: 2019182-02-4
- Formula: C18H29ClN2O3
- Molecular Weight:356.89
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Storage:
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2019182-02-4
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Appearance Solid
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Molecular Weight 356.89
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Formula C18H29ClN2O3
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Color White to off-white
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SMILES
O=C(N[C@H](C)[C@@H](O)C1=CC=CC=C1)[C@H](C)[C@@H](OC)[C@H]2NCCC2.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (280.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (248 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8020 mL | 14.0098 mL | 28.0195 mL | 70.0488 mL |
| 5 mM | 0.5604 mL | 2.8020 mL | 5.6039 mL | 14.0098 mL | |
| 10 mM | 0.2802 mL | 1.4010 mL | 2.8020 mL | 7.0049 mL | |
| 15 mM | 0.1868 mL | 0.9340 mL | 1.8680 mL | 4.6699 mL | |
| 20 mM | 0.1401 mL | 0.7005 mL | 1.4010 mL | 3.5024 mL | |
| 25 mM | 0.1121 mL | 0.5604 mL | 1.1208 mL | 2.8020 mL | |
| 30 mM | 0.0934 mL | 0.4670 mL | 0.9340 mL | 2.3350 mL | |
| 40 mM | 0.0700 mL | 0.3502 mL | 0.7005 mL | 1.7512 mL | |
| 50 mM | 0.0560 mL | 0.2802 mL | 0.5604 mL | 1.4010 mL | |
| 60 mM | 0.0467 mL | 0.2335 mL | 0.4670 mL | 1.1675 mL | |
| 80 mM | 0.0350 mL | 0.1751 mL | 0.3502 mL | 0.8756 mL | |
| 100 mM | 0.0280 mL | 0.1401 mL | 0.2802 mL | 0.7005 mL |