1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. Mal-EGGGG-PEG8-amide-bis(deoxyglucitol)

Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) 

Cat. No.: HY-48692 Purity: 99.89%
COA Handling Instructions

Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable ADC linker.

For research use only. We do not sell to patients.

Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) Chemical Structure

Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) Chemical Structure

CAS No. : 2360920-01-8

Size Price Stock Quantity
1 mg USD 339 In-stock
5 mg USD 746 In-stock
10 mg USD 1194 In-stock
25 mg USD 2388 In-stock
50 mg USD 3822 In-stock
100 mg   Get quote  
200 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Description

Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable ADC linker.

Molecular Weight

1391.38

Formula

C55H94N10O31

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC([C@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CNC(CNC(CNC(CNC([C@H](CCC(O)=O)NC(CN1C(C=CC1=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (71.87 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7187 mL 3.5936 mL 7.1871 mL
5 mM 0.1437 mL 0.7187 mL 1.4374 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.7187 mL 3.5936 mL 7.1871 mL 17.9678 mL
5 mM 0.1437 mL 0.7187 mL 1.4374 mL 3.5936 mL
10 mM 0.0719 mL 0.3594 mL 0.7187 mL 1.7968 mL
15 mM 0.0479 mL 0.2396 mL 0.4791 mL 1.1979 mL
20 mM 0.0359 mL 0.1797 mL 0.3594 mL 0.8984 mL
25 mM 0.0287 mL 0.1437 mL 0.2875 mL 0.7187 mL
30 mM 0.0240 mL 0.1198 mL 0.2396 mL 0.5989 mL
40 mM 0.0180 mL 0.0898 mL 0.1797 mL 0.4492 mL
50 mM 0.0144 mL 0.0719 mL 0.1437 mL 0.3594 mL
60 mM 0.0120 mL 0.0599 mL 0.1198 mL 0.2995 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Mal-EGGGG-PEG8-amide-bis(deoxyglucitol)
Cat. No.:
HY-48692
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