Mal-EGGGG-PEG8-amide-bis(deoxyglucitol)
Based on 1 Customer Validation
Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) (M67-0) is a cleavable ADC linker that can be used in the synthesis of ADCs.
For research use only. We do not sell to patients.
- Purity: 99.61%
- CAS No.: 2360920-01-8
- Formula: C55H94N10O31
- Molecular Weight:1391.38
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Biological Activity
Antibody-conjugated drugs (ADCs) consist of monoclonal antibodies, linkers and cytotoxic agents.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2360920-01-8
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Appearance Solid
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Molecular Weight 1391.38
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Formula C55H94N10O31
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Color White to off-white
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SMILES
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC([C@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CNC(CNC(CNC(CNC([C@H](CCC(O)=O)NC(CN1C(C=CC1=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
H2O : 100 mg/mL (71.87 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.7187 mL | 3.5936 mL | 7.1871 mL | 17.9678 mL |
| 5 mM | 0.1437 mL | 0.7187 mL | 1.4374 mL | 3.5936 mL | |
| 10 mM | 0.0719 mL | 0.3594 mL | 0.7187 mL | 1.7968 mL | |
| 15 mM | 0.0479 mL | 0.2396 mL | 0.4791 mL | 1.1979 mL | |
| 20 mM | 0.0359 mL | 0.1797 mL | 0.3594 mL | 0.8984 mL | |
| 25 mM | 0.0287 mL | 0.1437 mL | 0.2875 mL | 0.7187 mL | |
| 30 mM | 0.0240 mL | 0.1198 mL | 0.2396 mL | 0.5989 mL | |
| 40 mM | 0.0180 mL | 0.0898 mL | 0.1797 mL | 0.4492 mL | |
| 50 mM | 0.0144 mL | 0.0719 mL | 0.1437 mL | 0.3594 mL | |
| 60 mM | 0.0120 mL | 0.0599 mL | 0.1198 mL | 0.2995 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.