Mal-amido-PEG2-Val-Cit-PAB-PNP
Based on 1 Customer Validation
Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 98.40%
- CAS No.: 2112738-13-1
- Formula: C39H50N8O14
- Molecular Weight:854.86
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-20336
Mc-Val-Cit-PABC-PNP
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HY-12362
Val-cit-PAB-OH
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HY-41189
Fmoc-Val-Cit-PAB-PNP
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HY-78738
MC-Val-Cit-PAB
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HY-19318
Fmoc-Val-Cit-PAB
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HY-141142
Boc-Val-Cit-PAB-PNP
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HY-140145
Mal-PEG4-Val-Cit-PAB-PNP
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HY-141141
Boc-Val-Cit-PAB
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HY-140150
Azido-PEG3-Val-Cit-PAB-PNP
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HY-140149
Azido-PEG4-Val-Cit-PAB-OH
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HY-W038702
Boc-Val-Cit-OH
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HY-130944
Mal-PEG1-Val-Cit-PABC-OH
Biological Activity
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Protease Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2112738-13-1
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Appearance Solid
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Molecular Weight 854.86
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Formula C39H50N8O14
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Color White to off-white
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SMILES
O=C(NC1=CC=C(COC(OC2=CC=C(N(=O)=O)C=C2)=O)C=C1)[C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCNC(CCN(C3=O)C(C=C3)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (116.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1698 mL | 5.8489 mL | 11.6978 mL | 29.2446 mL |
| 5 mM | 0.2340 mL | 1.1698 mL | 2.3396 mL | 5.8489 mL | |
| 10 mM | 0.1170 mL | 0.5849 mL | 1.1698 mL | 2.9245 mL | |
| 15 mM | 0.0780 mL | 0.3899 mL | 0.7799 mL | 1.9496 mL | |
| 20 mM | 0.0585 mL | 0.2924 mL | 0.5849 mL | 1.4622 mL | |
| 25 mM | 0.0468 mL | 0.2340 mL | 0.4679 mL | 1.1698 mL | |
| 30 mM | 0.0390 mL | 0.1950 mL | 0.3899 mL | 0.9748 mL | |
| 40 mM | 0.0292 mL | 0.1462 mL | 0.2924 mL | 0.7311 mL | |
| 50 mM | 0.0234 mL | 0.1170 mL | 0.2340 mL | 0.5849 mL | |
| 60 mM | 0.0195 mL | 0.0975 mL | 0.1950 mL | 0.4874 mL | |
| 80 mM | 0.0146 mL | 0.0731 mL | 0.1462 mL | 0.3656 mL | |
| 100 mM | 0.0117 mL | 0.0585 mL | 0.1170 mL | 0.2924 mL |
Mal-amido-PEG2-Val-Cit-PAB-PNP Related Classifications
HY-140147 Related Classifications
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