Acid-PEG1-bis-PEG3-BCN
Acid-PEG1-bis-PEG3-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Acid-PEG1-bis-PEG3-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- Formula: C51H81N5O18
- Molecular Weight:1052.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1052.21
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Formula C51H81N5O18
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SMILES
O=C(NCCOCCOCCOCCNC(OC[C@@H]1[C@]2(CCC#CCC[C@]21[H])[H])=O)CCOCC(NC(COCC(O)=O)=O)COCCC(NCCOCCOCCOCCNC(OC[C@@H]3[C@]4(CCC#CCC[C@]43[H])[H])=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)