Mal-Sulfo-DBCO
Based on 1 publication(s) in Google Scholar
Mal-Sulfo-DBCO is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-Sulfo-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- CAS No.: 2028281-86-7
- Formula: C28H26N4O8S
- Molecular Weight:578.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Mal-Sulfo-DBCO
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Biological Activity
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Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2028281-86-7
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Molecular Weight 578.59
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Formula C28H26N4O8S
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SMILES
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCNC(C(S(=O)(O)=O)CNC(CCN(C4=O)C(C=C4)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Acta Biomater
Engineered bioorthogonal cell delivery system for in situ antimicrobial peptide recruitment during systemic bacterial infection. [Abstract]2025 Apr 10:S1742-7061(25)00265-X. PMID: 40220946
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)