1. Antibody-drug Conjugate/ADC Related Cytoskeleton Cell Cycle/DNA Damage
  2. Drug-Linker Conjugates for ADC Microtubule/Tubulin
  3. Aminobenzenesulfonic auristatin E-d8

Aminobenzenesulfonic auristatin E-d8 

Cat. No.: HY-145989S Purity: 98.02%
COA Handling Instructions

Aminobenzenesulfonic auristatin E-d8 is the deuterium labeled Aminobenzenesulfonic auristatin E. Aminobenzenesulfonic auristatin E is a drug-linker conjugate for ADC. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic[1][2].

For research use only. We do not sell to patients.

Aminobenzenesulfonic auristatin E-d<sub>8</sub> Chemical Structure

Aminobenzenesulfonic auristatin E-d8 Chemical Structure

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1 mg USD 960 In-stock
5 mg USD 2200 In-stock
10 mg USD 3350 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Aminobenzenesulfonic auristatin E-d8 is the deuterium labeled Aminobenzenesulfonic auristatin E. Aminobenzenesulfonic auristatin E is a drug-linker conjugate for ADC. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

761.05

Formula

C37H56D8N6O8S

Appearance

Solid

Color

White to off-white

SMILES

C[C@@H](C(N[S](=O)(C(C=C1)=CC=C1N)=O)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(C([2H])(C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])NC([C@@H](N(C)C)C(C)C)=O)=O)=O)OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Aminobenzenesulfonic auristatin E-d8
Cat. No.:
HY-145989S
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