Aminobenzenesulfonic auristatin E
Aminobenzenesulfonic auristatin E is a agent-linker conjugate for ADC. Aminobenzenesulfonic auristatin E has potent antitumor activity by using Auristatin E (a cytotoxic tubulin modifier), linked via the ADC linker Aminobenzenesulfonic.
For research use only. We do not sell to patients.
- CAS No.: 1800462-99-0
- Formula: C37H64N6O8S
- Molecular Weight:753.00
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
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Auristatin |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1800462-99-0
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Molecular Weight 753.00
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Formula C37H64N6O8S
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SMILES
C[C@@H](C(N[S](=O)(C(C=C1)=CC=C1N)=O)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@@H](N(C)C)C(C)C)=O)=O)=O)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
DMSO : 330 mg/mL (438.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3280 mL | 6.6401 mL | 13.2802 mL | 33.2005 mL |
| 5 mM | 0.2656 mL | 1.3280 mL | 2.6560 mL | 6.6401 mL | |
| 10 mM | 0.1328 mL | 0.6640 mL | 1.3280 mL | 3.3201 mL | |
| 15 mM | 0.0885 mL | 0.4427 mL | 0.8853 mL | 2.2134 mL | |
| 20 mM | 0.0664 mL | 0.3320 mL | 0.6640 mL | 1.6600 mL | |
| 25 mM | 0.0531 mL | 0.2656 mL | 0.5312 mL | 1.3280 mL | |
| 30 mM | 0.0443 mL | 0.2213 mL | 0.4427 mL | 1.1067 mL | |
| 40 mM | 0.0332 mL | 0.1660 mL | 0.3320 mL | 0.8300 mL | |
| 50 mM | 0.0266 mL | 0.1328 mL | 0.2656 mL | 0.6640 mL | |
| 60 mM | 0.0221 mL | 0.1107 mL | 0.2213 mL | 0.5533 mL | |
| 80 mM | 0.0166 mL | 0.0830 mL | 0.1660 mL | 0.4150 mL | |
| 100 mM | 0.0133 mL | 0.0664 mL | 0.1328 mL | 0.3320 mL |
Aminobenzenesulfonic auristatin E Related Classifications
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