1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. PC SPDP-NHS carbonate ester

PC SPDP-NHS carbonate ester 

Cat. No.: HY-140138
Handling Instructions

PC SPDP-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

PC SPDP-NHS carbonate ester Chemical Structure

PC SPDP-NHS carbonate ester Chemical Structure

CAS No. : 2279944-61-3

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Description

PC SPDP-NHS carbonate ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

608.64

Formula

C₂₅H₂₈N₄O₁₀S₂

CAS No.

2279944-61-3

SMILES

O=C(CCCOC1=CC([N+]([O-])=O)=C(C(C)OC(ON2C(CCC2=O)=O)=O)C=C1OC)NCCSSC3=NC=CC=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

PC SPDP-NHS carbonate esterADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product Name:
PC SPDP-NHS carbonate ester
Cat. No.:
HY-140138
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