4-N3Pfp-NHS ester
Based on 1 Customer Validation
4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 4-N3Pfp-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- Pureté: 97.95%
- CAS No.: 126695-58-7
- Formule: C11H4F4N4O4
- Masse moléculaire:332.17
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Stockage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Activité biologique
Description
IC50 & Target
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Non-cleavable Linker |
Chemical Information
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CAS No. 126695-58-7
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Appearance Solid
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Masse moléculaire 332.17
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Formule C11H4F4N4O4
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Color White to off-white
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SMILES
O=C(ON1C(CCC1=O)=O)C2=C(F)C(F)=C(N=[N+]=[N-])C(F)=C2F
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Pureté et documentation
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Fiche technique (243 KB)
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SDS (604 KB)
- English - EN (604 KB)
- Français - FR (604 KB)
- Deutsch - DE (604 KB)
- Norwegian - NO (604 KB)
- Español - ES (604 KB)
- Swedish - SV (604 KB)
- Italian - IT (604 KB)
- Korean - KR (604 KB)
- Portuguese - PT (604 KB)
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Instruction de manipulation (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)