Mal-PEG1-Val-Cit-PAB-PNP
Based on 1 Customer Validation
Mal-PEG1-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 98.41%
- CAS No.: 2249935-92-8
- Formula: C34H41N7O12
- Molecular Weight:739.73
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Anti-Cancer Compound Library
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Covalent Screening Library
HY-L036
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Biological Activity
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Protease Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2249935-92-8
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Appearance Solid
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Molecular Weight 739.73
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Formula C34H41N7O12
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Color White to off-white
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SMILES
O=[N+]([O-])C(C=C1)=CC=C1OC(OCC(C=C2)=CC=C2NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCN3C(C=CC3=O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (168.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.3518 mL | 6.7592 mL | 13.5184 mL | 33.7961 mL |
| 5 mM | 0.2704 mL | 1.3518 mL | 2.7037 mL | 6.7592 mL | |
| 10 mM | 0.1352 mL | 0.6759 mL | 1.3518 mL | 3.3796 mL | |
| 15 mM | 0.0901 mL | 0.4506 mL | 0.9012 mL | 2.2531 mL | |
| 20 mM | 0.0676 mL | 0.3380 mL | 0.6759 mL | 1.6898 mL | |
| 25 mM | 0.0541 mL | 0.2704 mL | 0.5407 mL | 1.3518 mL | |
| 30 mM | 0.0451 mL | 0.2253 mL | 0.4506 mL | 1.1265 mL | |
| 40 mM | 0.0338 mL | 0.1690 mL | 0.3380 mL | 0.8449 mL | |
| 50 mM | 0.0270 mL | 0.1352 mL | 0.2704 mL | 0.6759 mL | |
| 60 mM | 0.0225 mL | 0.1127 mL | 0.2253 mL | 0.5633 mL | |
| 80 mM | 0.0169 mL | 0.0845 mL | 0.1690 mL | 0.4225 mL | |
| 100 mM | 0.0135 mL | 0.0676 mL | 0.1352 mL | 0.3380 mL |
Mal-PEG1-Val-Cit-PAB-PNP Related Classifications
HY-140144 Related Classifications
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