2. Antibody-drug Conjugate/ADC Related
    PROTAC
  3. ADC Linker
    PROTAC Linkers
  4. Mal-PEG2-acid

Mal-PEG2-acid 

Cat. No.: HY-130442
Handling Instructions

Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Mal-PEG2-acid Chemical Structure

Mal-PEG2-acid Chemical Structure

CAS No. : 1374666-32-6

Size Price Stock
50 mg USD 100 Ask For Quote & Lead Time
100 mg USD 160 Ask For Quote & Lead Time
250 mg USD 280 Ask For Quote & Lead Time

* Please select Quantity before adding items.

Top Publications Citing Use of Products

View All ADC Linker Isoform Specific Products:

View All Isoforms
Cleavable Non-cleavable Acid Cleavable Disulfide Cleavable Protease Cleavable Glycosidase Cleavable Phosphatase Cleavable

View All PROTAC Linkers Isoform Specific Products:

View All Isoforms
PEGs Alkyl-Chain Alkyl/ether

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule[1]. Mal-PEG2-acid is also a PROTAC linker that can be used in the synthesis of PROTACs.

IC50 & Target

Non-cleavable

 

PEGs

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

257.24

Appearance

Solid

Formula

C11H15NO6
CAS No.
SMILES

O=C(O)CCOCCOCCN1C(C=CC1=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Mal-PEG2-acid1374666-32-6ADC LinkerPROTAC LinkersAntibody-drug conjugates linkerADClinkerprotacTubulysinInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Mal-PEG2-acid
Cat. No.:
HY-130442
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email address *

Phone number

 

Department *

Organization name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.