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Tubulysin 

Cat. No.: HY-128914
Handling Instructions

Tubulysin family of secondary metabolites are originally isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. These compounds are potent microtubule destabilizing agents with IC50 values in the picomolar range against many cancer cell lines, including those with multidrug resistant properties. Tubulysins have limited therapeutic utility due to severe toxicity, so Tubulysins are ideal candidates to be incorporated into molecule drug conjugate (SMDC) delivery system.

For research use only. We do not sell to patients.

Tubulysin Chemical Structure

Tubulysin Chemical Structure

CAS No. : 1943604-24-7

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Description

Tubulysin family of secondary metabolites are originally isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. These compounds are potent microtubule destabilizing agents with IC50 values in the picomolar range against many cancer cell lines, including those with multidrug resistant properties. Tubulysins have limited therapeutic utility due to severe toxicity, so Tubulysins are ideal candidates to be incorporated into molecule drug conjugate (SMDC) delivery system[1].

Molecular Weight

842.10

Formula

C₄₄H₆₇N₅O₉S

CAS No.

1943604-24-7

SMILES

O=C(O)[[email protected]@H](C)C[[email protected]@H](NC(C1=CSC([[email protected]](OC(C)=O)C[[email protected]@H](N(COC(CC(C)C)=O)C([[email protected]@H](NC([[email protected]@H]2N(C)CCCC2)=O)[[email protected]@H](C)CC)=O)C(C)C)=N1)=O)CC3=CC=C(C)C=C3

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Room temperature in continental US; may vary elsewhere

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Tubulysin
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