2. Antibody-drug Conjugate/ADC Related PROTAC
  3. ADC Linker PROTAC Linkers
  4. Amino-PEG11-OH

Amino-PEG11-OH is non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG11-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

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Amino-PEG11-OH

Amino-PEG11-OH Chemical Structure

CAS No. : 15332-94-2

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Amino-PEG11-OH Related Antibodies

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Description

Amino-PEG11-OH is non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG11-OH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

Non-cleavable Linker

 

PEGs

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Amino-PEG11-OH Related Antibodies
Masse moléculaire

501.61

Formule

C22H47NO11
CAS No.
SMILES

OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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Amino-PEG11-OH Related Classifications

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Keywords:

Amino-PEG11-OH15332-94-2ADC LinkerPROTAC LinkersAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Amino-PEG11-OH
Cat. No.:
HY-130298
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