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Cat. No.: HY-173633

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BrAc-Val-Ala

BrAc-Val-Ala is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as ABBV-969.

For research use only. We do not sell to patients.

Formula: C₁₀H₁₇BrN₂O₄
Molecular Weight:309.16

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

BrAc-Val-Ala Chemical Structure

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Use of MCE Products

One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity

Description

BrAc-Val-Ala is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as ABBV-969^[1].

All ADC Linkers Isoforms :

Chemical Information

Molecular Weight 309.16
Formula C₁₀H₁₇BrN₂O₄
SMILES

BrCC(N[C@@H](C(C)C)C(N[C@@H](C)C(O)=O)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

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Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. R. Berger, et al. 1660TiP First-in-human study of ABBV-969, a dual variable antibody-drug conjugate (ADC), in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC). Prostate cancerVolume 35, Supplement 2S1000-S1001September 2024.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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BrAc-Val-Ala

All ADC Linkers Isoforms