2. Antibody-drug Conjugate/ADC Related Cell Cycle/DNA Damage
  3. ADC Cytotoxin Topoisomerase
  4. NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT

NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (compound I) is a topoisomerase I inhibitor, which can be delivered to cells through conjugated antibody targeting, and has good ADC activity in vivo and in vitro.

For research use only. We do not sell to patients.

NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT Chemical Structure

NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT Chemical Structure

CAS No. : 2857037-69-3

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Other Forms of NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT:

NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT Related Antibodies

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Topoisomerase Topo I Topo II

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Description

NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (compound I) is a topoisomerase I inhibitor, which can be delivered to cells through conjugated antibody targeting, and has good ADC activity in vivo and in vitro[1].

Molecular Weight

473.48

Formula

C26H23N3O6
CAS No.
SMILES

NC12CC(C2)(C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(OCO8)=C8C=C73)C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT2857037-69-3ADC CytotoxinTopoisomeraseADC PayloadInhibitorinhibitorinhibit

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