1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. PPC-NHS ester

PPC-NHS ester (Synonyms: 2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoate)

Cat. No.: HY-W071006
Handling Instructions

PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

PPC-NHS ester Chemical Structure

PPC-NHS ester Chemical Structure

CAS No. : 107348-47-0

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Description

PPC-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Molecular Weight

326.39

Formula

C₁₃H₁₄N₂O₄S₂

CAS No.

107348-47-0

SMILES

CC(SSC1=NC=CC=C1)CC(ON2C(CCC2=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

PPC-NHS ester2,5-Dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)butanoateADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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Product name:
PPC-NHS ester
Cat. No.:
HY-W071006
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