Vc-MMAD
Based on 1 Customer Validation
Vc-MMAD consists the ADCs linker (Val-Cit) and potent tubulin inhibitor (MMAD). Vc-MMAD is a agent-linker conjugate for ADC.
For research use only. We do not sell to patients.
- Purity: 99.96%
- CAS No.: 1401963-17-4
- Formula: C70H104N12O14S
- Molecular Weight:1369.71
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
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Auristatin |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1401963-17-4
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Appearance Solid
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Molecular Weight 1369.71
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Formula C70H104N12O14S
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Color White to off-white
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SMILES
O=C1N(CCCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(COC(N([C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@H]([C@@H](CC(N3[C@@H](CCC3)[C@H](OC)[C@H](C(N[C@H](C4=NC=CS4)CC5=CC=CC=C5)=O)C)=O)OC)[C@@H](C)CC)C)=O)=O)C)=O)C=C2)=O)=O)=O)C(C=C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 160 mg/mL (116.81 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7301 mL | 3.6504 mL | 7.3008 mL | 18.2520 mL |
| 5 mM | 0.1460 mL | 0.7301 mL | 1.4602 mL | 3.6504 mL | |
| 10 mM | 0.0730 mL | 0.3650 mL | 0.7301 mL | 1.8252 mL | |
| 15 mM | 0.0487 mL | 0.2434 mL | 0.4867 mL | 1.2168 mL | |
| 20 mM | 0.0365 mL | 0.1825 mL | 0.3650 mL | 0.9126 mL | |
| 25 mM | 0.0292 mL | 0.1460 mL | 0.2920 mL | 0.7301 mL | |
| 30 mM | 0.0243 mL | 0.1217 mL | 0.2434 mL | 0.6084 mL | |
| 40 mM | 0.0183 mL | 0.0913 mL | 0.1825 mL | 0.4563 mL | |
| 50 mM | 0.0146 mL | 0.0730 mL | 0.1460 mL | 0.3650 mL | |
| 60 mM | 0.0122 mL | 0.0608 mL | 0.1217 mL | 0.3042 mL | |
| 80 mM | 0.0091 mL | 0.0456 mL | 0.0913 mL | 0.2282 mL | |
| 100 mM | 0.0073 mL | 0.0365 mL | 0.0730 mL | 0.1825 mL |
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