Cys-MC-VC-PAB-MMAE
Based on 1 Customer Validation
Cys-MC-VC-PAB-MMAE consists a cleavable ADC linker (Cys-MC-VC-PAB) and a potent tubulin inhibitor (MMAE). Cys-MC-VC-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 98.23%
- CAS No.: 3051855-32-1
- Formula: C71H112N12O17S
- Molecular Weight:1437.78
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Chemical Information
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CAS No. 3051855-32-1
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Appearance Solid
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Molecular Weight 1437.78
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Formula C71H112N12O17S
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Color White to off-white
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SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN4C(C(CC4=O)SC[C@H](N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (69.55 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6955 mL | 3.4776 mL | 6.9552 mL | 17.3879 mL |
| 5 mM | 0.1391 mL | 0.6955 mL | 1.3910 mL | 3.4776 mL | |
| 10 mM | 0.0696 mL | 0.3478 mL | 0.6955 mL | 1.7388 mL | |
| 15 mM | 0.0464 mL | 0.2318 mL | 0.4637 mL | 1.1592 mL | |
| 20 mM | 0.0348 mL | 0.1739 mL | 0.3478 mL | 0.8694 mL | |
| 25 mM | 0.0278 mL | 0.1391 mL | 0.2782 mL | 0.6955 mL | |
| 30 mM | 0.0232 mL | 0.1159 mL | 0.2318 mL | 0.5796 mL | |
| 40 mM | 0.0174 mL | 0.0869 mL | 0.1739 mL | 0.4347 mL | |
| 50 mM | 0.0139 mL | 0.0696 mL | 0.1391 mL | 0.3478 mL | |
| 60 mM | 0.0116 mL | 0.0580 mL | 0.1159 mL | 0.2898 mL |
Cys-MC-VC-PAB-MMAE Related Classifications
HY-171822 Related Classifications
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