SuO-Glu-Val-Cit-PAB-MMAE
Based on 1 Customer Validation
SuO-Glu-Val-Cit-PAB-MMAE (NHS-Glutarate-Val-Cit-PAB-MMAE) consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity: 99.38%
- CAS No.: 1895916-24-1
- Formula: C67H103N11O17
- Molecular Weight:1334.60
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Storage:
-80°C, protect from light
* The compound is unstable in solutions, freshly prepared is recommended.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
More
Biological Activity
|
Auristatin |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1895916-24-1
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Appearance Solid
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Molecular Weight 1334.60
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Formula C67H103N11O17
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Color White to off-white
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SMILES
CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC(ON4C(CCC4=O)=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O)C
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Synonyms
NHS-Glutarate-Val-Cit-PAB-MMAE
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Shipping
Shipping with dry ice.
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Storage
-80°C, protect from light
* The compound is unstable in solutions, freshly prepared is recommended.
Solvent & Solubility
DMSO : 100 mg/mL (74.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.7493 mL | 3.7464 mL | 7.4929 mL | 18.7322 mL |
| 5 mM | 0.1499 mL | 0.7493 mL | 1.4986 mL | 3.7464 mL | |
| 10 mM | 0.0749 mL | 0.3746 mL | 0.7493 mL | 1.8732 mL | |
| 15 mM | 0.0500 mL | 0.2498 mL | 0.4995 mL | 1.2488 mL | |
| 20 mM | 0.0375 mL | 0.1873 mL | 0.3746 mL | 0.9366 mL | |
| 25 mM | 0.0300 mL | 0.1499 mL | 0.2997 mL | 0.7493 mL | |
| 30 mM | 0.0250 mL | 0.1249 mL | 0.2498 mL | 0.6244 mL | |
| 40 mM | 0.0187 mL | 0.0937 mL | 0.1873 mL | 0.4683 mL | |
| 50 mM | 0.0150 mL | 0.0749 mL | 0.1499 mL | 0.3746 mL | |
| 60 mM | 0.0125 mL | 0.0624 mL | 0.1249 mL | 0.3122 mL |
SuO-Glu-Val-Cit-PAB-MMAE Related Classifications
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