1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. SuO-Glu-Val-Cit-PAB-MMAE

SuO-Glu-Val-Cit-PAB-MMAE 

Cat. No.: HY-130989
Handling Instructions

SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

SuO-Glu-Val-Cit-PAB-MMAE Chemical Structure

SuO-Glu-Val-Cit-PAB-MMAE Chemical Structure

CAS No. : 1895916-24-1

Size Price Stock
1 mg USD 550 Ask For Quote & Lead Time
5 mg USD 1200 Ask For Quote & Lead Time
10 mg USD 2400 Ask For Quote & Lead Time

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Top Publications Citing Use of Products
  • Biological Activity

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Description

SuO-Glu-Val-Cit-PAB-MMAE consists a cleavable ADC linker (SuO-Glu-Val-Cit-PAB) and a potent tubulin inhibitor (MMAE). SuO-Glu-Val-Cit-PAB-MMAE can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Auristatin

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1334.60

Formula

C67H103N11O17

CAS No.
SMILES

CC[[email protected]](C)[[email protected]@H]([[email protected]@H](CC(N1[[email protected]@H](CCC1)[[email protected]@H]([[email protected]@H](C)C(N[[email protected]](C)[[email protected]@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([[email protected]](C(C)C)NC([[email protected]](C(C)C)N(C(OCC3=CC=C(NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CCCC(ON4C(CCC4=O)=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (149.86 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7493 mL 3.7464 mL 7.4929 mL
5 mM 0.1499 mL 0.7493 mL 1.4986 mL
10 mM 0.0749 mL 0.3746 mL 0.7493 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Product Name:
SuO-Glu-Val-Cit-PAB-MMAE
Cat. No.:
HY-130989
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