Mal-VC-PAB-PNP
Based on 1 Customer Validation
Mal-VC-PAB-PNP is a cleavable ADC linker. Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.03%
- CAS 番号: 1096584-62-1
- 分子式: C32H37N7O11
- 分子量:695.68
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-20336
Mc-Val-Cit-PABC-PNPADC Linker -
HY-15575
VcMMAEDrug-Linker Conjugate for ADC -
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Val-cit-PAB-OHADC Linker -
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Fmoc-Val-Cit-PAB-PNPADC Linker -
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MC-Val-Cit-PABADC Linker -
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Fmoc-Val-Cit-PABADC Linker -
HY-141142
Boc-Val-Cit-PAB-PNPADC Linker -
HY-140145
Mal-PEG4-Val-Cit-PAB-PNPADC linker -
HY-136314
DBCO-PEG4-VC-PAB-MMAEDrug-Linker Conjugate for ADC -
HY-141141
Boc-Val-Cit-PABADC Linker -
HY-140150
Azido-PEG3-Val-Cit-PAB-PNPADC Linker -
HY-15575G
VcMMAE (GMP)Drug-Linker Conjugate for ADC
生物活性
製品説明
IC50 & Target
[1]|
Cleavable Linker |
体外実験
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1096584-62-1
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性状 Solid
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分子量 695.68
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分子式 C32H37N7O11
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Color White to off-white
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SMILES
O=[N+]([O-])C(C=C1)=CC=C1OC(OCC(C=C2)=CC=C2NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCN3C(C=CC3=O)=O)=O)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 125 mg/mL (179.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4374 mL | 7.1872 mL | 14.3744 mL | 35.9361 mL |
| 5 mM | 0.2875 mL | 1.4374 mL | 2.8749 mL | 7.1872 mL | |
| 10 mM | 0.1437 mL | 0.7187 mL | 1.4374 mL | 3.5936 mL | |
| 15 mM | 0.0958 mL | 0.4791 mL | 0.9583 mL | 2.3957 mL | |
| 20 mM | 0.0719 mL | 0.3594 mL | 0.7187 mL | 1.7968 mL | |
| 25 mM | 0.0575 mL | 0.2875 mL | 0.5750 mL | 1.4374 mL | |
| 30 mM | 0.0479 mL | 0.2396 mL | 0.4791 mL | 1.1979 mL | |
| 40 mM | 0.0359 mL | 0.1797 mL | 0.3594 mL | 0.8984 mL | |
| 50 mM | 0.0287 mL | 0.1437 mL | 0.2875 mL | 0.7187 mL | |
| 60 mM | 0.0240 mL | 0.1198 mL | 0.2396 mL | 0.5989 mL | |
| 80 mM | 0.0180 mL | 0.0898 mL | 0.1797 mL | 0.4492 mL | |
| 100 mM | 0.0144 mL | 0.0719 mL | 0.1437 mL | 0.3594 mL |
Mal-VC-PAB-PNP 関連分類
HY-148461 関連分類
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