Mal-VC-PAB-PNP
Based on 1 Customer Validation
Mal-VC-PAB-PNP is a cleavable ADC linker. Mal-VC-PAB-PNP can be used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- CAS No.: 1096584-62-1
- Formula: C32H37N7O11
- Molecular Weight:695.68
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1096584-62-1
-
Appearance Solid
-
Molecular Weight 695.68
-
Formula C32H37N7O11
-
Color White to off-white
-
SMILES
O=[N+]([O-])C(C=C1)=CC=C1OC(OCC(C=C2)=CC=C2NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCN3C(C=CC3=O)=O)=O)=O)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (179.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (274 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4374 mL | 7.1872 mL | 14.3744 mL | 35.9361 mL |
| 5 mM | 0.2875 mL | 1.4374 mL | 2.8749 mL | 7.1872 mL | |
| 10 mM | 0.1437 mL | 0.7187 mL | 1.4374 mL | 3.5936 mL | |
| 15 mM | 0.0958 mL | 0.4791 mL | 0.9583 mL | 2.3957 mL | |
| 20 mM | 0.0719 mL | 0.3594 mL | 0.7187 mL | 1.7968 mL | |
| 25 mM | 0.0575 mL | 0.2875 mL | 0.5750 mL | 1.4374 mL | |
| 30 mM | 0.0479 mL | 0.2396 mL | 0.4791 mL | 1.1979 mL | |
| 40 mM | 0.0359 mL | 0.1797 mL | 0.3594 mL | 0.8984 mL | |
| 50 mM | 0.0287 mL | 0.1437 mL | 0.2875 mL | 0.7187 mL | |
| 60 mM | 0.0240 mL | 0.1198 mL | 0.2396 mL | 0.5989 mL | |
| 80 mM | 0.0180 mL | 0.0898 mL | 0.1797 mL | 0.4492 mL | |
| 100 mM | 0.0144 mL | 0.0719 mL | 0.1437 mL | 0.3594 mL |
Mal-VC-PAB-PNP Related Classifications
HY-148461 Related Classifications
Powered by Bioz