1. Cytoskeleton
    Cell Cycle/DNA Damage
    Antibody-drug Conjugate/ADC Related
  2. Microtubule/Tubulin
    Drug-Linker Conjugates for ADC
  3. OSu-Glu-VC-PAB-MMAD

OSu-Glu-VC-PAB-MMAD 

Cat. No.: HY-136315
Handling Instructions

OSu-Glu-VC-PAB-MMAD is a drug-linker conjugate for ADC with potent antitumor activity by using MMAD (a potent tubulin inhibitor), linked via the cleavable ADC linker OSu-Glu-VC-PAB.

For research use only. We do not sell to patients.

OSu-Glu-VC-PAB-MMAD Chemical Structure

OSu-Glu-VC-PAB-MMAD Chemical Structure

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Description

OSu-Glu-VC-PAB-MMAD is a drug-linker conjugate for ADC with potent antitumor activity by using MMAD (a potent tubulin inhibitor), linked via the cleavable ADC linker OSu-Glu-VC-PAB.

IC50 & Target

Auristatin

 

Molecular Weight

1387.68

Formula

C₆₉H₁₀₂N₁₂O₁₆S

SMILES

O=C(CCC1=O)N1OC(CCCC(N[[email protected]@H](C(C)C)C(NC(CCCNC(N)=O)C(NC2=CC=C(COC(N(C)[[email protected]](C(C)C)C(N[[email protected]@H](C(C)C)C(N(C)[[email protected]@H]([[email protected]@H](C)CC)[[email protected]](OC)CC(N3[[email protected]]([[email protected]](OC)[[email protected]@H](C)C(N[[email protected]@H](CC4=CC=CC=C4)C5=NC=CS5)=O)CCC3)=O)=O)=O)=O)C=C2)=O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

OSu-Glu-VC-PAB-MMADMicrotubule/TubulinDrug-Linker Conjugates for ADCInhibitorinhibitorinhibit

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OSu-Glu-VC-PAB-MMAD
Cat. No.:
HY-136315
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