MAL-di-EG-Val-Cit-PAB-MMAF
Based on 1 Customer Validation
MAL-di-EG-Val-Cit-PAB-MMAF consists the ADCs linker (MAL-di-EG-Val-Cit-PAB) and potent tubulin polymerization blocker (MMAF, Monomethyl auristatin F).
For research use only. We do not sell to patients.
- Purity : 95.99%
- Formula: C72H110N12O19
- Molecular Weight:1447.71
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Storage:
4°C, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
Description
IC50 & Target
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Auristatin |
Chemical Information
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Appearance Solid
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Molecular Weight 1447.71
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Formula C72H110N12O19
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Color White to off-white
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SMILES
CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@@H](CC(N2[C@@H](CCC2)[C@@H]([C@@H](C)C(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)OC)=O)OC)=O)=O)=O)C=C1)=O)=O)NC(CCOCCOCCNC(CCN4C(C=CC4=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* The compound is unstable in solutions, freshly prepared is recommended.
Solvent & Solubility
In Vitro:
DMSO : 230 mg/mL (158.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6907 mL | 3.4537 mL | 6.9075 mL | 17.2687 mL |
| 5 mM | 0.1381 mL | 0.6907 mL | 1.3815 mL | 3.4537 mL | |
| 10 mM | 0.0691 mL | 0.3454 mL | 0.6907 mL | 1.7269 mL | |
| 15 mM | 0.0460 mL | 0.2302 mL | 0.4605 mL | 1.1512 mL | |
| 20 mM | 0.0345 mL | 0.1727 mL | 0.3454 mL | 0.8634 mL | |
| 25 mM | 0.0276 mL | 0.1381 mL | 0.2763 mL | 0.6907 mL | |
| 30 mM | 0.0230 mL | 0.1151 mL | 0.2302 mL | 0.5756 mL | |
| 40 mM | 0.0173 mL | 0.0863 mL | 0.1727 mL | 0.4317 mL | |
| 50 mM | 0.0138 mL | 0.0691 mL | 0.1381 mL | 0.3454 mL | |
| 60 mM | 0.0115 mL | 0.0576 mL | 0.1151 mL | 0.2878 mL | |
| 80 mM | 0.0086 mL | 0.0432 mL | 0.0863 mL | 0.2159 mL | |
| 100 mM | 0.0069 mL | 0.0345 mL | 0.0691 mL | 0.1727 mL |
MAL-di-EG-Val-Cit-PAB-MMAF Related Classifications
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