1. Antibody-drug Conjugate/ADC Related
    Cytoskeleton
    Cell Cycle/DNA Damage
  2. Drug-Linker Conjugates for ADC
    Microtubule/Tubulin
  3. MC-Val-Cit-PAB-MMAF

MC-Val-Cit-PAB-MMAF 

Cat. No.: HY-112786
Handling Instructions

MC-Val-Cit-PAB-MMAF is a drug-linker conjugate for ADC with antitumor activity by using the tubulin inhibitor, MMAF, linked via cathepsin cleavable MC-Val-Cit-PAB.

For research use only. We do not sell to patients.

MC-Val-Cit-PAB-MMAF Chemical Structure

MC-Val-Cit-PAB-MMAF Chemical Structure

CAS No. : 863971-17-9

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Description

MC-Val-Cit-PAB-MMAF is a drug-linker conjugate for ADC with antitumor activity by using the tubulin inhibitor, MMAF, linked via cathepsin cleavable MC-Val-Cit-PAB.

IC50 & Target[1]

Auristatin

 

Molecular Weight

1330.61

Formula

C₆₈H₁₀₃N₁₁O₁₆

CAS No.

863971-17-9

SMILES

OC([[email protected]](CC1=CC=CC=C1)NC([[email protected]](C)[[email protected]]([[email protected]@]2([H])N(CCC2)C(C[[email protected]@H](OC)[[email protected]@]([[email protected]@H](C)CC)([H])N(C)C([[email protected]](C(C)C)NC([[email protected]](C(C)C)N(C)C(OCC3=CC=C(NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NC(CCCCCN4C(C=CC4=O)=O)=O)=O)=O)C=C3)=O)=O)=O)=O)OC)=O)=O

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

MC-Val-Cit-PAB-MMAFDrug-Linker Conjugates for ADCMicrotubule/TubulinInhibitorinhibitorinhibit

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MC-Val-Cit-PAB-MMAF
Cat. No.:
HY-112786
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