MC-Val-Cit-PAB-rifabutin
Based on 1 Customer Validation
MC-Val-Cit-PAB-rifabutin is a agent-linker conjugate for ADC with potent antitumor activity by using rifabutin (an DNA-dependent RNA polymerase inhibitor), linked via the ADC linker MC-Val-Cit-PAB.
For research use only. We do not sell to patients.
- Purity: 95.33%
- CAS No.: 2055900-34-8
- Formula: C74H101ClN10O17
- Molecular Weight:1438.10
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
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Traditional Cytotoxic Agents |
Chemical Information
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CAS No. 2055900-34-8
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Appearance Solid
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Molecular Weight 1438.10
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Formula C74H101ClN10O17
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Color Brown to reddish brown
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SMILES
O=C1C2=C(C(C)=C(C3=C2C4=NC5(NC4=C(C3=O)N6)CC[N+](CC(C)C)(CC5)CC7=CC=C(C=C7)NC([C@@H](NC([C@@H](NC(CCCCCN8C(C=CC8=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)O)O[C@]1(C)O/C=C/[C@H](OC)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@H]([C@H](/C=C/C=C(C)\C6=O)C)O.[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 20 mg/mL (13.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6954 mL | 3.4768 mL | 6.9536 mL | 17.3840 mL |
| 5 mM | 0.1391 mL | 0.6954 mL | 1.3907 mL | 3.4768 mL | |
| 10 mM | 0.0695 mL | 0.3477 mL | 0.6954 mL | 1.7384 mL |