1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. MB-VC-MGBA

MB-VC-MGBA 

Cat. No.: HY-136289
Handling Instructions

MB-VC-MGBA is a drug-linker conjugate for ADC with potent antitumor activity by using MGBA (minor-groove-binding DNA-alkylating agent), linked via the ADC linker MB-VC.

For research use only. We do not sell to patients.

MB-VC-MGBA Chemical Structure

MB-VC-MGBA Chemical Structure

CAS No. : 932744-62-2

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Description

MB-VC-MGBA is a drug-linker conjugate for ADC with potent antitumor activity by using MGBA (minor-groove-binding DNA-alkylating agent), linked via the ADC linker MB-VC[1].

IC50 & Target[1]

Duocarmycins

 

Molecular Weight

1101.64

Formula

C₅₆H₆₅ClN₁₂O₁₀

CAS No.

932744-62-2

SMILES

ClC[[email protected]](C1)C(C2=CC=CC=C2C(OC(N(CC3)CCN3C)=O)=C4)=C4N1C(C5=CC6=CC(NC(C(C=C7)=CC=C7NC([[email protected]](CCCNC(N)=O)NC([[email protected]](C(C)C)NCCNC(CCCN(C8=O)C(C=C8)=O)=O)=O)=O)=O)=CC=C6N5)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

MB-VC-MGBADrug-Linker Conjugates for ADCDuocarmycinsADCMGBADNA-alkylatingMBVCInhibitorinhibitorinhibit

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MB-VC-MGBA
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