932744-62-2
Chemical Structure
MB-VC-MGBA
- CAS No.: 932744-62-2
- Formula:C56H65ClN12O10
- Molecular Weight:1101.64
IUPAC Name: (S)-1-(chloromethyl)-3-(5-(4-((S)-2-((S)-2-((2-(4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanamido)ethyl)amino)-3-methylbutanamido)-5-ureidopentanamido)benzamido)-1H-indole-2-carbonyl)-2,3-dihydro-1H-benzo[e]indol-5-yl 4-methylpiperazine-1-carboxylate
InChIKey: LWUVZRWVARAEMO-MUYWJSLASA-N
SMILES: ClC[C@H](C1)C(C2=CC=CC=C2C(OC(N(CC3)CCN3C)=O)=C4)=C4N1C(C5=CC6=CC(NC(C(C=C7)=CC=C7NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NCCNC(CCCN(C8=O)C(C=C8)=O)=O)=O)=O)=O)=CC=C6N5)=O
Biological Activity: MB-VC-MGBA is a agent-linker conjugate for ADC with potent antitumor activity by using MGBA (minor-groove-binding DNA-alkylating agent), linked via the ADC linker MB-VC[1].
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MB-VC-MGBA | MB-VC-MGBA is a agent-linker conjugate for ADC with potent antitumor activity by using MGBA (minor-groove-binding DNA-alkylating agent), linked via the ADC linker MB-VC. | |||||||||||||||||||||
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Keywords