MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D

Name: MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D
Brand: MedChemExpress
SKU: HY-145488
Rating: 4.5 (1 reviews)

Cat. No.: HY-145488 Purity: 98.92%: FAQs
Data Sheet SDS COA Handling Instructions

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MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D Chemical Structure

CAS No. : 2222445-87-4

Size	Price	Stock	Quantity
1 mg	USD 690	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 1680	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 2700	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 5500	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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•Related Small Molecules:

•Related Proteins:

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View All Isoforms

Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

Biological Activity
Purity & Documentation
References
Customer Review

Description

MethylCBI-azaindole-benzamide-MOM-Boc-ethylenediamine-D is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

Cleavable Linker

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

859.36

Formula

C₄₄H₅₁ClN₆O₁₀

CAS No.

2222445-87-4

Appearance

Solid

Color

White to light yellow

SMILES

ClC[C@H]1C2=C(C=C(C3=CC=CC(C)=C32)OC(N(CCOCCO)CCN(C)C(OC(C)(C)C)=O)=O)N(C1)C(C4=CN(C=C(C=C5)NC(C6=CC=C(C=C6)OCOC)=O)C5=N4)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Purity: 98.92%

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Data Sheet (271 KB) SDS (0 KB)

COA (256 KB) HNMR (366 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [Content Brief]