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Cat. No.: HY-177502

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NHS-cBu-Cit-PAB

NHS-cBu-Cit-PAB is an intermediate of ADC linker. NHS-cBu-Cit-PAB can be used for synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

CAS No.: 1799660-11-9
Formula: C₂₃H₂₉N₅O₈
Molecular Weight:503.51

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

NHS-cBu-Cit-PAB Chemical Structure

CAS No.: 1799660-11-9

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Biological Activity

Description

NHS-cBu-Cit-PAB is an intermediate of ADC linker. NHS-cBu-Cit-PAB can be used for synthesis of antibody-drug conjugates (ADCs)^[1].

All ADC Linkers Isoforms :

Chemical Information

CAS No. 1799660-11-9
Molecular Weight 503.51
Formula C₂₃H₂₉N₅O₈
SMILES

O=C(C1(C(N[C@H](C(NC2=CC=C(CO)C=C2)=O)CCCNC(N)=O)=O)CCC1)ON3C(CCC3=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wei B, et al. Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity. J Med Chem. 2018 Feb 8;61(3):989-1000. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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NHS-cBu-Cit-PAB

All ADC Linkers Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

NHS-cBu-Cit-PAB Related Classifications

HY-177502 Related Classifications