AcLys-PABC-VC-Aur0101 intermediate-1
AcLys-PABC-VC-Aur0101 intermediate-1 is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate.
For research use only. We do not sell to patients.
- CAS No.: 1609108-48-6
- Formula: C41H53N7O8
- Molecular Weight:771.90
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cleavable Linker |
Chemical Information
-
CAS No. 1609108-48-6
-
Molecular Weight 771.90
-
Formula C41H53N7O8
-
SMILES
OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CCCCNC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
DMSO : 100 mg/mL (129.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2955 mL | 6.4775 mL | 12.9550 mL | 32.3876 mL |
| 5 mM | 0.2591 mL | 1.2955 mL | 2.5910 mL | 6.4775 mL | |
| 10 mM | 0.1296 mL | 0.6478 mL | 1.2955 mL | 3.2388 mL | |
| 15 mM | 0.0864 mL | 0.4318 mL | 0.8637 mL | 2.1592 mL | |
| 20 mM | 0.0648 mL | 0.3239 mL | 0.6478 mL | 1.6194 mL | |
| 25 mM | 0.0518 mL | 0.2591 mL | 0.5182 mL | 1.2955 mL | |
| 30 mM | 0.0432 mL | 0.2159 mL | 0.4318 mL | 1.0796 mL | |
| 40 mM | 0.0324 mL | 0.1619 mL | 0.3239 mL | 0.8097 mL | |
| 50 mM | 0.0259 mL | 0.1296 mL | 0.2591 mL | 0.6478 mL | |
| 60 mM | 0.0216 mL | 0.1080 mL | 0.2159 mL | 0.5398 mL | |
| 80 mM | 0.0162 mL | 0.0810 mL | 0.1619 mL | 0.4048 mL | |
| 100 mM | 0.0130 mL | 0.0648 mL | 0.1296 mL | 0.3239 mL |