Amino-PEG2-C2-acid
Based on 1 Customer Validation
Amino-PEG2-C2-acid is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-PEG2-C2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Purity : 99.72%
- CAS No.: 791028-27-8
- 화학식: C7H15NO4
- 분자량:177.20
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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HY-W021787
NH2-PEG4-CH2CH2COOH -
HY-W040165
Amino-PEG3-C2-acid -
HY-140189
Amino-PEG3-CH2COOHPROTAC Linker -
HY-W008005
Amino-PEG4-alcohol -
HY-W021401
Amino-PEG3-C2-Azido -
HY-W007545
NH2-PEG3PROTAC Linker -
HY-126942
Amino-PEG6-alcoholPROTAC Linkers -
HY-140213
Azido-PEG2-C2-aminePROTAC Linker -
HY-W040257
NH2-PEG6-CH2CH2COOH -
HY-130166
Amino-PEG9-acidADC/PROTAC Linker -
HY-W019798
NH2-PEG8-acid -
HY-140193
Amino-PEG4-BocPROTAC Linkers
All PROTAC Linkers Isoforms
More
Biological Activity
제품 설명
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Cleavable Linker |
PEGs |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 791028-27-8
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Appearance Solid
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분자량 177.20
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화학식 C7H15NO4
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Color White to off-white
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SMILES
O=C(O)CCOCCOCCN
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 2 mg/mL (11.29 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (266 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.6433 mL | 28.2167 mL | 56.4334 mL | 141.0835 mL |
| 5 mM | 1.1287 mL | 5.6433 mL | 11.2867 mL | 28.2167 mL | |
| 10 mM | 0.5643 mL | 2.8217 mL | 5.6433 mL | 14.1084 mL |
Amino-PEG2-C2-acid Related Classifications
HY-W040168 Related Classifications
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