TCO-PEG1-Val-Cit-PABC-PNP
TCO-PEG1-Val-Cit-PABC-PNP is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). TCO-PEG1-Val-Cit-PABC-PNP is a click chemistry reagent, which contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
For research use only. We do not sell to patients.
- Formula: C39H53N7O12
- Molecular Weight:811.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Protease Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 811.88
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Formula C39H53N7O12
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SMILES
O=C(OC1/C=C/CCCCC1)NCCOCCC(N[C@H](C(N[C@H](C(NC2=CC=C(C=C2)COC(OC3=CC=C([N+]([O-])=O)C=C3)=O)=O)CCCNC(N)=O)=O)C(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TCO-PEG1-Val-Cit-PABC-PNP Related Classifications
HY-136100 Related Classifications
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