Mal-C2-Gly3-EDA-PNU-159682
Based on 1 Customer Validation
Mal-C2-Gly3-EDA-PNU-159682, a agent-linker conjugate for ADC, consists a cleavable ADC linker Mal-C2-Gly3-EDA and a potent ADC cytotoxin PNU-159682.
For research use only. We do not sell to patients.
- Purity: 93.43%
- CAS No.: 2259318-53-9
- Formula: C46H53N7O18
- Molecular Weight:991.95
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All Drug-Linker Conjugates for ADC Isoforms
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Biological Activity
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2259318-53-9
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Appearance Solid
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Molecular Weight 991.95
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Formula C46H53N7O18
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Color Orange to red
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SMILES
O=C([C@@]1(O)C[C@H](O[C@H]2C[C@@]3([H])[C@]([C@H](C)O2)([H])O[C@]4([H])[C@@H](OC)OCCN43)C5=C(O)C6=C(C(C7=CC=CC(OC)=C7C6=O)=O)C(O)=C5C1)NCCNC(CNC(CNC(CNC(CCN8C(C=CC8=O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (100.81 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (256 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0081 mL | 5.0406 mL | 10.0812 mL | 25.2029 mL |
| 5 mM | 0.2016 mL | 1.0081 mL | 2.0162 mL | 5.0406 mL | |
| 10 mM | 0.1008 mL | 0.5041 mL | 1.0081 mL | 2.5203 mL | |
| 15 mM | 0.0672 mL | 0.3360 mL | 0.6721 mL | 1.6802 mL | |
| 20 mM | 0.0504 mL | 0.2520 mL | 0.5041 mL | 1.2601 mL | |
| 25 mM | 0.0403 mL | 0.2016 mL | 0.4032 mL | 1.0081 mL | |
| 30 mM | 0.0336 mL | 0.1680 mL | 0.3360 mL | 0.8401 mL | |
| 40 mM | 0.0252 mL | 0.1260 mL | 0.2520 mL | 0.6301 mL | |
| 50 mM | 0.0202 mL | 0.1008 mL | 0.2016 mL | 0.5041 mL | |
| 60 mM | 0.0168 mL | 0.0840 mL | 0.1680 mL | 0.4200 mL | |
| 80 mM | 0.0126 mL | 0.0630 mL | 0.1260 mL | 0.3150 mL | |
| 100 mM | 0.0101 mL | 0.0504 mL | 0.1008 mL | 0.2520 mL |
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